Nice colours etc, however, the header doesn't match the horizontal centering you have for the rest of the site... I know why u haven't centered the header (because of the brush image), so I would left align the body/content of the site to match.
Also, although the image is nice, perhaps scale the brush image down in size a little, I am running 1920 x 1200 and even then the content starts two thirds down the page. Scale back the branding of your site a little and focus more on the content.
I find using a grid template / system helps. With your current design, your content starts well below the fold.
Test your site in 1024 x 768 / 1280 x 1024.
Also, in your left hand menu, it still says 'portofolio'
One last thing, it may be just my personal preference, but I don't think the white overlay when a page loads adds anything to either the design or functionality. Let people see the page while its loading, I don't need the whole page to be loaded to start using it. For me, its more of a 'here's something I know how to do' type of inclusion. In my opinion, save a few kb and get rid of it.
Lastly, pay a little more attention to your typography. A little more leading in the body copy would be perfect.
Otherwise, looking good.